Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 17/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19924361 | 1.00 | PIK3CD (0.65) | PIK3CDKCNH2HRH3 | |
| SCHEMBL19346941 | 0.99 | PIK3CD (0.65) | PIK3CDKCNH2HRH3 | |
| SCHEMBL17458367 | 0.89 | PIK3CD (0.67) | PIK3CDKCNH2HRH3 | |
| SCHEMBL17458365 | 0.89 | PIK3CD (0.67) | PIK3CDKCNH2HRH3 | |
| SCHEMBL17458344 | 0.86 | PIK3CD (0.67) | PIK3CD | |
| SCHEMBL17458428 | 0.85 | PIK3CD (0.68) | PIK3CD | |
| SCHEMBL17458148 | 0.85 | PIK3CD (0.64) | PIK3CDKCNH2HRH3 | |
| SCHEMBL17458147 | 0.85 | PIK3CD (0.64) | PIK3CDKCNH2HRH3 | |
| SCHEMBL17457980 | 0.84 | PIK3CD (0.64) | PIK3CDKCNH2HRH3 | |
| SCHEMBL17457978 | 0.84 | PIK3CD (0.64) | PIK3CDKCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160960-B1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2021-10-13 | — | — | EP | disclosed |
| US-20180065953-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065953-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | PIK3CA, PIK3R5, PIK3R4 | PIK3CD 8/4885KCNH2 1754/4885HRH3 1591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.