Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19924656 | 0.79 | BRD4 (1.00) | BRD4 | |
| SCHEMBL19924871 | 0.78 | BRD4 (0.67) | BRD4 | |
| SCHEMBL19927785 | 0.78 | BRD4 (1.00) | BRD4 | |
| SCHEMBL19924596 | 0.77 | BRD4 (0.86) | BRD4 | |
| SCHEMBL19924911 | 0.76 | BRD4 (0.84) | BRD4 | |
| SCHEMBL19924601 | 0.76 | BRD4 (1.00) | BRD4 | |
| SCHEMBL19936769 | 0.76 | BRD4 (0.82) | BRD4 | |
| SCHEMBL19924912 | 0.76 | BRD4 (1.00) | BRD4 | |
| SCHEMBL19937096 | 0.75 | BRD4 (1.00) | BRD4 | |
| SCHEMBL19924921 | 0.75 | BRD4 (1.00) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507283-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF AUTOIMMUNE OR INFLAMMATORY DISEASES OR CANCERS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2019-07-10 | — | — | EP | disclosed |
| WO-2018041947-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF AUTOIMMUNE OR INFLAMMATORY DISEASES OR CANCERS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2018-03-08 | — | — | WO | disclosed |