Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15833705 | 0.86 | PRMT5 (0.89) | PRMT5WDR77 | |
| SCHEMBL15943919 | 0.85 | PRMT5 (1.00) | PRMT5WDR77 | |
| SCHEMBL15825869 | 0.84 | PRMT5 (1.00) | PRMT5WDR77 | |
| SCHEMBL15943948 | 0.84 | PRMT5 (1.00) | PRMT5WDR77 | |
| SCHEMBL15943946 | 0.82 | PRMT5 (0.83) | PRMT5WDR77 | |
| SCHEMBL15944043 | 0.81 | PRMT5 (1.00) | PRMT5WDR77 | |
| SCHEMBL15943791 | 0.80 | PRMT5 (1.00) | PRMT5WDR77 | |
| SCHEMBL15943826 | 0.80 | PRMT5 (1.00) | PRMT5WDR77 | |
| SCHEMBL15833553 | 0.80 | PRMT5 (1.00) | PRMT5WDR77 | |
| SCHEMBL15943977 | 0.80 | PRMT5 (0.86) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9908887-B2 | PRMT5 inhibitors and uses thereof | Epizyme, Inc. (US) | 2018-03-06 | — | — | US | disclosed |