Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16818085 | 0.96 | MAP3K5 (1.00) | MAP3K5AKT1 | |
| SCHEMBL16818025 | 0.95 | MAP3K5 (1.00) | MAP3K5AKT1 | |
| SCHEMBL19928345 | 0.94 | MAP3K5 (0.89) | MAP3K5AKT1 | |
| SCHEMBL16818037 | 0.93 | MAP3K5 (1.00) | MAP3K5AKT1 | |
| SCHEMBL16818040 | 0.91 | MAP3K5 (1.00) | MAP3K5AKT1 | |
| SCHEMBL15811892 | 0.91 | MAP3K5 (1.00) | MAP3K5AKT1 | |
| SCHEMBL15811987 | 0.91 | MAP3K5 (1.00) | MAP3K5AKT1 | |
| SCHEMBL15812002 | 0.91 | MAP3K5 (1.00) | MAP3K5AKT1 | |
| SCHEMBL19927936 | 0.90 | MAP3K5 (0.75) | MAP3K5AKT1 | |
| SCHEMBL16818006 | 0.90 | MAP3K5 (1.00) | MAP3K5AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9908875-B2 | Apoptosis signal-regulating kinase inhibitors | GILEAD SCIENCES, INC. (US) | 2018-03-06 | — | — | US | disclosed |