⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1997325 | 0.66 | — | — | |
| SCHEMBL2051532 | 0.62 | — | — | |
| Bromide SCHEMBL21804716 | 0.60 | — | — | |
| Hydrochloric Acid SCHEMBL4832902 | 0.60 | — | — | |
| SCHEMBL13719381 | 0.28 | — | — | |
| SCHEMBL14136744 | 0.27 | — | — | |
| Methane SCHEMBL23929073 | 0.23 | — | — | |
| SCHEMBL16553398 | 0.23 | — | — | |
| SCHEMBL25271841 | 0.23 | — | — | |
| SCHEMBL8433806 | 0.23 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210401845-A1 | METHODS AND COMPOSITIONS FOR KRAS INHIBITORS | UNIV TEXAS (US) | 2021-12-30 | — | — | US | disclosed |
| US-11141418-B1 | Methods and compositions for KRAS inhibitors | THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-10-12 | — | — | US | disclosed |
| US-9362509-B2 | Aryloxy-phthalocyanines of group IV metals | SAUDI BASIC INDUSTRIES CORPORATION (SA) | 2016-06-07 | — | — | US | disclosed |
| EP-2948463-A2 | ARYLOXY-PHTHALOCYANINES OF GROUP IV METALS | Saudi Basic Industries Corporation (SA) | 2015-12-02 | — | — | EP | disclosed |
| EP-2945954-A1 | ARYLOXY-PHTHALOCYANINES OF GROUP III METALS | Saudi Basic Industries Corporation (SA) | 2015-11-25 | — | — | EP | disclosed |
| US-9187496-B2 | 5,5-fused arylene or heteroarylene hepatitis C virus inhibitors | IDENIX PHARMACEUTICALS LLC (US) | 2015-11-17 | — | — | US | disclosed |
| US-20150255732-A1 | ARYLOXY-PHTHALOCYANINES OF GROUP IV METALS | SAUDI BASIC INDUSTRIES CORPORATION (SA) | 2015-09-10 | — | — | US | disclosed |
| EP-2892976-A2 | PROCESS FOR MANUFACTURE OF CONJUGATED POLYMER COMPOSITIONS FOR SOLAR CELL APPLICATIONS | Saudi Basic Industries Corporation (SA) | 2015-07-15 | — | — | EP | disclosed |
| EP-2892975-A2 | CONJUGATED POLYMER COMPOSITION FOR SOLAR CELL AND FLEXIBLE ELECTRONICS APPLICATIONS | Saudi Basic Industries Corporation (SA) | 2015-07-15 | — | — | EP | disclosed |
| US-9073935-B2 | Substituted benzylspiroindolin-2-one analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M1 | VANDERBILT UNIVERSITY (US) | 2015-07-07 | — | — | US | disclosed |
| EP-2691093-A1 | METHODS FOR TREATING DRUG-RESISTANT HEPATITIS C VIRUS INFECTION WITH A 5,5-FUSED ARYLENE OR HETEROARYLENE HEPATITIS C VIRUS INHIBITOR | IDENIX Pharmaceuticals, Inc. (US) | 2014-02-05 | — | — | EP | disclosed |
| WO-2013071201-A1 | SUBSTITUTED BENZYLSPIROINDOLIN-2-ONE ANALOGS AS POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | VANDERBILT UNIVERSITY (US) | 2013-05-16 | — | — | WO | disclosed |
| US-20130123236-A1 | SUBSTITUTED BENZYLSPIROINDOLIN-2-ONE ANALOGS AS POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | VANDERBILT UNIVERSITY (US) | 2013-05-16 | — | — | US | disclosed |
| US-20130071352-A1 | 5,5-FUSED ARYLENE OR HETEROARYLENE HEPATITIS C VIRUS INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2013-03-21 | — | — | US | disclosed |
| US-8362068-B2 | 5,5-fused arylene or heteroarylene hepatitis C virus inhibitors | IDENIX PHARMACEUTICALS, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| EP-2513113-A1 | 5,5-FUSED ARYLENE OR HETEROARYLENE HEPATITIS C VIRUS INHIBITORS | IDENIX Pharmaceuticals, Inc. (US) | 2012-10-24 | — | — | EP | disclosed |
| US-20120252721-A1 | METHODS FOR TREATING DRUG-RESISTANT HEPATITIS C VIRUS INFECTION WITH A 5,5-FUSED ARYLENE OR HETEROARYLENE HEPATITIS C VIRUS INHIBITOR | IDENIX PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | US | disclosed |
| WO-2012135581-A1 | METHODS FOR TREATING DRUG-RESISTANT HEPATITIS C VIRUS INFECTION WITH A 5,5-FUSED ARYLENE OR HETEROARYLENE HEPATITIS C VIRUS INHIBITOR | IDENIX PHARMACEUTICALS, INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| US-20110150827-A1 | 5,5-FUSED ARYLENE OR HETEROARYLENE HEPATITIS C VIRUS INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2011-06-23 | — | — | US | disclosed |
| WO-2011075615-A1 | 5,5-FUSED ARYLENE OR HETEROARYLENE HEPATITIS C VIRUS INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2011-06-23 | — | — | WO | disclosed |