Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 12/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19930659 | 0.88 | BRD4 (0.50) | BRD4TLR9TLR8TLR7 | |
| SCHEMBL21916713 | 0.87 | BRD4 (0.51) | BRD4TLR9TLR8TLR7 | |
| SCHEMBL19930860 | 0.85 | BRD4 (0.42) | BRD4TLR9TLR8TLR7 | |
| SCHEMBL16651032 | 0.85 | BRD4 (0.47) | BRD4 | |
| SCHEMBL29848666 | 0.85 | BRD4 (0.47) | BRD4 | |
| SCHEMBL29848937 | 0.85 | BRD4 (0.51) | BRD4 | |
| SCHEMBL16651107 | 0.85 | BRD4 (0.51) | BRD4 | |
| SCHEMBL29848802 | 0.84 | BRD4 (0.47) | BRD4 | |
| SCHEMBL16650972 | 0.84 | BRD4 (0.47) | BRD4 | |
| SCHEMBL19931220 | 0.84 | BRD4 (0.42) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134364-A2 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |
| EP-3640241-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-04-22 | — | — | EP | disclosed |
| EP-3290407-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc (US) | 2018-03-07 | — | — | EP | disclosed |