Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 17/20 | 0.51 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.51 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.49 |
| ▸ | BRD7 | Q9NPI1 | 3/20 | 0.49 |
| ▸ | BRD2 | P25440 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25043384 | 0.89 | BRD4 (0.50) | BRD4BRDTBRD9BRD7BRD2 | |
| SCHEMBL20094747 | 0.85 | BRD4 (0.56) | BRD4 | |
| SCHEMBL19931260 | 0.82 | BRD4 (0.49) | BRD4BRDTBRD9BRD7BRD2 | |
| SCHEMBL19931296 | 0.81 | BRD4 (0.73) | BRD4 | |
| SCHEMBL21915886 | 0.80 | BRD4 (0.42) | BRD4 | |
| SCHEMBL16650797 | 0.80 | BRD4 (0.71) | BRD4BRDT | |
| SCHEMBL29848989 | 0.80 | BRD4 (0.71) | BRD4BRDT | |
| SCHEMBL16658000 | 0.80 | BRD4 (0.68) | BRD4BRDT | |
| SCHEMBL19930886 | 0.79 | BRD4 (0.46) | BRD4BRDTBRD9BRD7BRD2 | |
| SCHEMBL21915992 | 0.79 | BRD4 (0.49) | BRD4BRDTBRD9BRD7BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3290407-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc (US) | 2018-03-07 | — | — | EP | disclosed |