Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 13/20 | 0.68 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21916731 | 0.90 | BRD4 (0.56) | BRD4MAPK14MAPK8 | |
| SCHEMBL16651765 | 0.86 | BRD4 (0.75) | BRD4CREBBPMAPK14MAPK8 | |
| SCHEMBL19931157 | 0.86 | BRD4 (0.72) | BRD4CREBBPMAPK14 | |
| SCHEMBL21998333 | 0.85 | BRD4 (0.66) | BRD4CREBBPMAPK14MAPK8 | |
| SCHEMBL16651455 | 0.85 | BRD4 (0.73) | BRD4CREBBP | |
| SCHEMBL19931267 | 0.85 | BRD4 (0.74) | BRD4CREBBPMAPK14MAPK8 | |
| SCHEMBL25043182 | 0.84 | BRD4 (0.74) | BRD4CREBBPMAPK14MAPK8 | |
| SCHEMBL19931348 | 0.83 | BRD4 (0.79) | BRD4CREBBPMAPK14MAPK8 | |
| SCHEMBL19931090 | 0.83 | BRD4 (0.68) | BRD4CREBBPMAPK14 | |
| SCHEMBL19931507 | 0.82 | BRD4 (0.47) | BRD4MAPK14MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134364-A2 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |
| EP-3640241-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-04-22 | — | — | EP | disclosed |
| EP-3290407-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc (US) | 2018-03-07 | — | — | EP | disclosed |