SCHEMBL19930837

SCHEMBL19930837

CCSc1ccc(OCC2CC2)c(-c2cn(C)c(=O)c3occc23)c1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 20/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19930948 0.93 BRD4 (0.47) BRD4
SCHEMBL25042171 0.91 BRD4 (0.52) BRD4
SCHEMBL19930909 0.86 BRD4 (0.48) BRD4
SCHEMBL19930803 0.85 BRD4 (0.51) BRD4
SCHEMBL19930841 0.85 BRD4 (0.51) BRD4
SCHEMBL16650451 0.84 BRD4 (0.68) BRD4
SCHEMBL16649668 0.83 BRD4 (0.68) BRD4
SCHEMBL16650232 0.81 BRD4 (0.70) BRD4
SCHEMBL21916076 0.81 BRD4 (0.60) BRD4
SCHEMBL25042980 0.81 BRD4 (0.48) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4134364-A2 BROMODOMAIN INHIBITORS Celgene Quanticel Research, Inc. (US) 2023-02-15 EP disclosed
EP-3640241-A1 BROMODOMAIN INHIBITORS Celgene Quanticel Research, Inc. (US) 2020-04-22 EP disclosed
EP-3290407-A1 BROMODOMAIN INHIBITORS Celgene Quanticel Research, Inc (US) 2018-03-07 EP disclosed