Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 10/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16650020 | 0.87 | BRD4 (1.00) | BRD4CREBBPMAPK8 | |
| SCHEMBL19931348 | 0.86 | BRD4 (0.79) | BRD4CREBBPMAPK8 | |
| SCHEMBL25043277 | 0.85 | BRD4 (0.78) | BRD4CREBBPMAPK8 | |
| SCHEMBL16650113 | 0.85 | BRD4 (1.00) | BRD4CREBBPMAPK8 | |
| SCHEMBL16657976 | 0.85 | BRD4 (0.77) | BRD4CREBBPMAPK8 | |
| SCHEMBL16651193 | 0.84 | BRD4 (0.74) | BRD4CREBBPMAPK8 | |
| SCHEMBL16650744 | 0.84 | BRD4 (0.94) | BRD4CREBBPMAPK8 | |
| SCHEMBL19931267 | 0.83 | BRD4 (0.74) | BRD4CREBBPMAPK8 | |
| SCHEMBL16650946 | 0.81 | BRD4 (0.94) | BRD4CREBBPMAPK8 | |
| SCHEMBL19931225 | 0.81 | BRD4 (0.73) | BRD4CREBBPMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640241-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-04-22 | — | — | EP | disclosed |
| EP-3290407-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc (US) | 2018-03-07 | — | — | EP | disclosed |