Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.39 |
| ▸ | MERTK | Q12866 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 11/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | GAS6 | Q14393 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21915917 | 0.81 | BRD4 (0.39) | BRD4CREBBPBRD9 | |
| SCHEMBL16650976 | 0.81 | BRD4 (0.51) | BRD4CREBBP | |
| SCHEMBL25043154 | 0.80 | CREBBP (0.40) | EGFRFGFR1TYRO3MERTKBRD4 | |
| SCHEMBL19930955 | 0.80 | CREBBP (0.36) | BRD4CREBBP | |
| SCHEMBL29848717 | 0.79 | CREBBP (0.47) | BRD4CREBBP | |
| SCHEMBL29849034 | 0.79 | BRD4 (0.43) | BRD4CREBBP | |
| SCHEMBL16650869 | 0.79 | CREBBP (0.47) | BRD4CREBBP | |
| SCHEMBL16651118 | 0.79 | BRD4 (0.43) | BRD4CREBBP | |
| SCHEMBL19930978 | 0.77 | BRD4 (0.35) | BRD4CREBBP | |
| SCHEMBL16651476 | 0.76 | CREBBP (0.48) | BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134364-A2 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |
| EP-3290407-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc (US) | 2018-03-07 | — | — | EP | disclosed |