Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 18/20 | 0.58 |
| ▸ | BRD9 | Q9H8M2 | 4/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19930977 | 0.85 | BRD4 (0.59) | BRD4BRD9RXRA | |
| SCHEMBL25042230 | 0.85 | BRD4 (0.63) | BRD4BRD9RXRA | |
| SCHEMBL16650438 | 0.83 | BRD4 (0.78) | BRD4BRD9 | |
| SCHEMBL19931466 | 0.83 | BRD4 (0.56) | BRD4BRD9RXRA | |
| SCHEMBL19931086 | 0.82 | BRD4 (0.55) | BRD4BRD9 | |
| SCHEMBL16651502 | 0.82 | BRD4 (0.65) | BRD4BRD9 | |
| SCHEMBL29848953 | 0.82 | BRD4 (0.65) | BRD4BRD9 | |
| SCHEMBL19931085 | 0.81 | BRD4 (0.54) | BRD4BRD9 | |
| SCHEMBL16650409 | 0.73 | BRD4 (1.00) | BRD4RXRA | |
| SCHEMBL19931004 | 0.73 | BRD4 (0.74) | BRD4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640241-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-04-22 | — | — | EP | disclosed |
| EP-3290407-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc (US) | 2018-03-07 | — | — | EP | disclosed |