Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 18/20 | 0.42 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.40 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16651222 | 0.81 | BRD4 (0.52) | BRD4BRDT | |
| SCHEMBL29848980 | 0.81 | BRD4 (0.52) | BRD4BRDT | |
| SCHEMBL19931276 | 0.79 | BRD4 (0.53) | BRD4BRD9BRD7BRD2BRDT | |
| SCHEMBL21915992 | 0.78 | BRD4 (0.49) | BRD4BRD9BRD7BRD2BRDT | |
| SCHEMBL29849040 | 0.73 | BRD4 (0.60) | BRD4BRDT | |
| SCHEMBL16650496 | 0.73 | BRD4 (0.60) | BRD4BRDT | |
| SCHEMBL19931524 | 0.72 | BRD4 (0.43) | BRD4BRD9BRD7BRD2BRDT | |
| SCHEMBL21916090 | 0.72 | BRD4 (0.53) | BRD4 | |
| SCHEMBL19930886 | 0.71 | BRD4 (0.46) | BRD4BRD9BRD7BRD2BRDT | |
| SCHEMBL19931116 | 0.70 | BRD4 (0.52) | BRD4BRD9BRD7BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640241-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-04-22 | — | — | EP | disclosed |
| EP-3290407-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc (US) | 2018-03-07 | — | — | EP | disclosed |