⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19933410 | 0.90 | — | — | |
| SCHEMBL19933444 | 0.86 | — | — | |
| SCHEMBL19933479 | 0.84 | — | — | |
| SCHEMBL19933437 | 0.84 | — | — | |
| SCHEMBL19933478 | 0.83 | EGLN1 (0.44) | — | |
| SCHEMBL19933468 | 0.82 | EGLN1 (0.34) | — | |
| SCHEMBL19933502 | 0.76 | TMPRSS4 (0.34) | — | |
| SCHEMBL19933382 | 0.75 | — | — | |
| SCHEMBL19933373 | 0.74 | CNR2 (0.40) | — | |
| SCHEMBL19933506 | 0.73 | VEGFA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180065933-A1 | DEUTERIUM-ENRICHED HYPOXIA-INDUCIBLE FACTOR PROLYL HYDROXYLASE ENZYME INHIBITORS | AKEBIA THERAPEUTICS, INC. (US) | 2018-03-08 | — | — | US | disclosed |