Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20365824 | 0.96 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDHTTKMT2AMEN1 | |
| SCHEMBL21767237 | 0.95 | SMN1; SMN2 (0.45) | SMN1; SMN2HPGDHTTKMT2AMEN1 | |
| SCHEMBL19732523 | 0.93 | SMN1; SMN2 (0.51) | SMN1; SMN2HPGDHTTKMT2AFAAH | |
| SCHEMBL17885935 | 0.92 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDHTTKMT2AFAAH | |
| SCHEMBL15763867 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2HPGDHTTKMT2AMEN1 | |
| SCHEMBL19732507 | 0.90 | SMN1; SMN2 (0.51) | SMN1; SMN2HPGDHTTKMT2AFAAH | |
| SCHEMBL17145176 | 0.90 | HPGD (0.40) | SMN1; SMN2HPGDHTTKMT2AMEN1 | |
| SCHEMBL20008742 | 0.90 | SMN1; SMN2 (0.48) | SMN1; SMN2HPGDHTTKMT2AMEN1 | |
| SCHEMBL12690424 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2HPGDHTTKMT2AMEN1 | |
| SCHEMBL30837144 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2HPGDHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045385-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. (US) | 2018-03-08 | — | — | WO | disclosed |