Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.54 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.54 |
| ▸ | PTPRC | P08575 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.53 |
| ▸ | FEN1 | P39748 | 6/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12330295 | 0.96 | TNKS (0.57) | TNKSTNKS2PTPRCPTPN1AKR1C3 | |
| SCHEMBL23173084 | 0.88 | AKR1C3 (0.58) | TNKSTNKS2AKR1C3AKR1C2FEN1 | |
| SCHEMBL13703908 | 0.88 | AKR1C3 (0.58) | TNKSTNKS2AKR1C3AKR1C2FEN1 | |
| SCHEMBL257611 | 0.85 | AKR1C3 (0.53) | AKR1C3AKR1C2FEN1ALOX5APAKR1B10 | |
| SCHEMBL27388542 | 0.84 | TNKS (0.53) | TNKSTNKS2PTPRCPTPN1FEN1 | |
| SCHEMBL14365640 | 0.82 | AKR1C3 (0.54) | AKR1C3AKR1C2FEN1ALOX5APAKR1B10 | |
| SCHEMBL10018722 | 0.82 | AKR1C3 (0.54) | AKR1C3AKR1C2FEN1ALOX5APAKR1B10 | |
| SCHEMBL26974251 | 0.82 | AKR1C3 (0.54) | AKR1C3AKR1C2FEN1ALOX5APAKR1B10 | |
| SCHEMBL16850562 | 0.82 | PTPRC (0.58) | TNKSTNKS2PTPRCPTPN1FEN1 | |
| SCHEMBL17951222 | 0.82 | PTPRC (0.58) | TNKSTNKS2PTPRCPTPN1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935513-B1 | LIQUID-CRYSTALLINE MEDIA, COMPONENTS FOR HIGH-FREQUENCY TECHNOLOGY, AND MESOGENIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2018-03-07 | — | — | EP | disclosed |