⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29239631 | 0.81 | — | — | |
| SCHEMBL1378574 | 0.79 | — | — | |
| SCHEMBL7211173 | 0.79 | CTSC (0.41) | — | |
| SCHEMBL1679977 | 0.77 | — | — | |
| SCHEMBL8693761 | 0.77 | — | — | |
| SCHEMBL24881405 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL3125591 | 0.77 | — | — | |
| SCHEMBL7685277 | 0.77 | — | — | |
| SCHEMBL20864018 | 0.75 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL1858724 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640528-B2 | Macrolides with modified desosamine sugars and uses thereof | PRESIDENT AND FELLOWS OF HAVARD COLLEGE (US) | 2020-05-05 | — | — | US | disclosed |
| US-20180066008-A1 | MACROLIDES WITH MODIFIED DESOSAMINE SUGARS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-03-08 | — | — | US | disclosed |