Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.62 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 13/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27725502 | 0.88 | DDB1 (0.52) | DDB1CRBNCYP19A1MMP2MMP9 | |
| SCHEMBL19586342 | 0.77 | CRBN (1.00) | DDB1CRBNMMP2MMP9ALDH1A1 | |
| SCHEMBL1398152 | 0.75 | CRBN (0.71) | DDB1CRBNALDH1A1MAPK1TDP1 | |
| SCHEMBL28302324 | 0.75 | DDB1 (0.43) | DDB1CRBNALDH1A1CYP3A4TSHR | |
| SCHEMBL16347174 | 0.74 | CETP (0.50) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL1399003 | 0.74 | DDB1 (0.55) | DDB1CRBNCYP3A4MAPK1 | |
| SCHEMBL16345546 | 0.73 | CETP (0.51) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL16344798 | 0.73 | CETP (0.51) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL16345450 | 0.73 | CETP (0.51) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL27767596 | 0.72 | CETP (0.47) | DDB1CRBNALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2943201-B1 | 3-(5-SUBSTITUTED-4-OXOQUINAZOLIN-3(4H)-YL)-3-DEUTERO-PIPERIDINE-2,6-DIONE DERIVATIVES | DEUTERX LLC (US) | 2018-03-07 | — | — | EP | disclosed |