SCHEMBL19936985

SCHEMBL19936985

CCCc1cccc(Cn2ccnc2-c2cc(C)c(=O)n(C)c2)c1F

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19936986 0.84 BRD4 (0.76) BRD4
SCHEMBL19924932 0.81 BRD4 (0.85) BRD4
SCHEMBL19924914 0.80 BRD4 (1.00) BRD4
SCHEMBL19924947 0.79 BRD4 (0.69) BRD4
SCHEMBL19925242 0.79 BRD4 (0.77) BRD4
SCHEMBL19937039 0.79 BRD4 (0.71) BRD4
SCHEMBL19925233 0.78 BRD4 (0.73) BRD4
SCHEMBL19924931 0.77 BRD4 (0.80) BRD4
SCHEMBL19924912 0.77 BRD4 (1.00) BRD4
SCHEMBL19927785 0.77 BRD4 (1.00) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018041964-A1 IMIDAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF AUTOIMMUNE OR INFLAMMATORY DISEASES OR CANCERS GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) 2018-03-08 WO disclosed