SCHEMBL19937013

SCHEMBL19937013

Cc1cc(-c2nc(C=O)cn2Cc2ccccc2)cn(C)c1=O

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19937046 0.86 BRD4 (1.00) BRD4
SCHEMBL19924933 0.86 BRD4 (1.00) BRD4
SCHEMBL19924900 0.84 BRD4 (0.78) BRD4
SCHEMBL19924903 0.84 BRD4 (1.00) BRD4
SCHEMBL19924935 0.84 BRD4 (1.00) BRD4
SCHEMBL19936932 0.82 BRD4 (1.00) BRD4
SCHEMBL4882456 0.82 BRD4 (0.49) BRD4
SCHEMBL19924918 0.81 BRD4 (1.00) BRD4
SCHEMBL19924938 0.81 BRD4 (0.88) BRD4
SCHEMBL19924960 0.81 BRD4 (0.71) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018041964-A1 IMIDAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF AUTOIMMUNE OR INFLAMMATORY DISEASES OR CANCERS GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) 2018-03-08 WO disclosed