Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 20/20 | 0.79 |
| ▸ | NSD2 | O96028 | 1/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.74 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.74 |
| ▸ | BID | P55957 | 1/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.74 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.74 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.74 |
| ▸ | ASPH | Q12797 | 1/20 | 0.74 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.74 |
| ▸ | BAD | Q92934 | 1/20 | 0.74 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.74 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.74 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19939499 | 0.97 | BCL2 (0.78) | BCL2NSD2ADORA3CYP2C9ADRA2C | |
| SCHEMBL28669114 | 0.94 | BCL2 (0.83) | BCL2NSD2ADORA3CYP2C9ADRA2C | |
| SCHEMBL28668842 | 0.93 | BCL2 (0.90) | BCL2NSD2ADORA3CYP2C9ADRA2C | |
| SCHEMBL28674531 | 0.93 | BCL2 (0.74) | BCL2NSD2ADORA3CYP2C9ADRA2C | |
| SCHEMBL28930476 | 0.93 | BCL2 (0.76) | BCL2NSD2ADORA3CYP2C9ADRA2C | |
| SCHEMBL19939509 | 0.93 | BCL2 (0.78) | BCL2NSD2ADORA3CYP2C9ADRA2C | |
| SCHEMBL19940513 | 0.92 | BCL2 (0.76) | BCL2NSD2ADORA3CYP2C9ADRA2C | |
| SCHEMBL19940333 | 0.91 | BCL2 (0.82) | BCL2NSD2ADORA3CYP2C9ADRA2C | |
| SCHEMBL19939589 | 0.90 | BCL2 (0.90) | BCL2NSD2ADORA3CYP2C9ADRA2C | |
| SCHEMBL19939573 | 0.90 | BCL2 (0.73) | BCL2NSD2ADORA3CYP2C9ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641897-B | Bcl-2 selective inhibitors, their preparation and use | 北京赛林泰医药技术有限公司 | 2021-12-07 | — | — | CN | disclosed |
| CN-109293656-A | Bcl-2 selective depressant and its preparation and use | 北京赛林泰医药技术有限公司 | 2019-02-01 | — | — | CN | disclosed |
| WO-2018041248-A1 | BCL-2 SELECTIVE INHIBITOR AND PREPARATION AND USE THEREOF | 北京赛林泰医药技术有限公司 | 2018-03-08 | — | — | WO | disclosed |