Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 19/20 | 0.63 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19940521 | 0.92 | BCL2 (0.59) | BCL2 | |
| SCHEMBL19940272 | 0.91 | BCL2 (0.77) | BCL2BCL2L1 | |
| SCHEMBL19940291 | 0.90 | BCL2 (0.61) | BCL2BCL2L1 | |
| SCHEMBL19939521 | 0.89 | BCL2 (0.75) | BCL2BCL2L1 | |
| SCHEMBL19940313 | 0.88 | BCL2 (0.63) | BCL2BCL2L1 | |
| SCHEMBL19939594 | 0.88 | BCL2 (0.69) | BCL2BCL2L1 | |
| SCHEMBL19940256 | 0.87 | BCL2 (0.62) | BCL2BCL2L1 | |
| SCHEMBL19940511 | 0.86 | BCL2 (0.75) | BCL2BCL2L1 | |
| SCHEMBL19940263 | 0.85 | BCL2 (0.70) | BCL2 | |
| Hydrochloric Acid SCHEMBL28679337 | 0.85 | BCL2 (0.69) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018041248-A1 | BCL-2 SELECTIVE INHIBITOR AND PREPARATION AND USE THEREOF | 北京赛林泰医药技术有限公司 | 2018-03-08 | — | — | WO | disclosed |