Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 19/20 | 0.60 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19940722 | 1.00 | TLR8 (0.60) | TLR8TLR7NLRP3 | |
| SCHEMBL18125192 | 0.91 | TLR8 (0.61) | TLR8TLR7NLRP3 | |
| SCHEMBL18923203 | 0.91 | TLR8 (0.61) | TLR8TLR7NLRP3 | |
| SCHEMBL18109286 | 0.90 | TLR8 (0.74) | TLR8TLR7NLRP3 | |
| SCHEMBL18109289 | 0.90 | TLR8 (0.74) | TLR8TLR7NLRP3 | |
| SCHEMBL18109714 | 0.89 | TLR8 (0.75) | TLR8TLR7NLRP3 | |
| SCHEMBL18109715 | 0.89 | TLR8 (0.75) | TLR8TLR7NLRP3 | |
| SCHEMBL19991825 | 0.89 | TLR8 (0.59) | TLR8TLR7NLRP3 | |
| SCHEMBL18109542 | 0.89 | TLR8 (0.75) | TLR8TLR7NLRP3 | |
| SCHEMBL18109545 | 0.89 | TLR8 (0.75) | TLR8TLR7NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045150-A1 | 4,6-DIAMINO-PYRIDO[3,2-D]PYRIMIDINE DERIVATIES AS TOLL LIKE RECEPTOR MODULATORS | GILEAD SCIENCES, INC. (US) | 2018-03-08 | — | — | WO | disclosed |