Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 18/20 | 0.64 |
| ▸ | CNR2 | P34972 | 18/20 | 0.64 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.48 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507802 | 0.83 | OPRL1 (0.67) | CNR1CNR2OPRL1 | |
| SCHEMBL4506313 | 0.80 | CNR1 (0.79) | CNR1CNR2 | |
| SCHEMBL1985825 | 0.78 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL1985342 | 0.78 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL1984625 | 0.77 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL4524003 | 0.77 | CNR1 (0.72) | CNR1CNR2 | |
| SCHEMBL4519778 | 0.77 | CNR1 (0.72) | CNR1CNR2 | |
| SCHEMBL3742041 | 0.76 | CNR1 (0.57) | CNR1CNR2OPRL1 | |
| SCHEMBL3740310 | 0.76 | CNR1 (0.55) | CNR1CNR2OPRL1 | |
| SCHEMBL4513948 | 0.76 | CNR2 (0.70) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602656-B1 | PYRAZOLE DERIVATIVES HAVING AFFINITY FOR CB1 AND/OR CB2 RECEPTORS | NEUROSCIENZE PHARMANESS S C A R L (IT) | 2011-06-29 | — | — | EP | claimed |