Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 15/20 | 0.63 |
| ▸ | CDK8 | P49336 | 5/20 | 0.34 |
| ▸ | CCNC | P24863 | 3/20 | 0.34 |
| ▸ | CDK19 | Q9BWU1 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16617315 | 0.91 | PTGER3 (0.68) | PTGER3CDK8CCNCCDK19 | |
| SCHEMBL16617313 | 0.91 | PTGER3 (0.68) | PTGER3CDK8CCNCCDK19 | |
| SCHEMBL16617680 | 0.85 | PTGER3 (0.69) | PTGER3CDK8CCNCCDK19 | |
| SCHEMBL16617681 | 0.85 | PTGER3 (0.69) | PTGER3CDK8CCNCCDK19 | |
| SCHEMBL16617140 | 0.80 | PTGER3 (0.68) | PTGER3CDK8CCNCCDK19 | |
| SCHEMBL16617137 | 0.80 | PTGER3 (0.68) | PTGER3CDK8CCNCCDK19 | |
| SCHEMBL16617915 | 0.78 | PTGER3 (1.00) | PTGER3 | |
| SCHEMBL16617916 | 0.78 | PTGER3 (1.00) | PTGER3 | |
| SCHEMBL16617784 | 0.75 | PTGER3 (0.69) | PTGER3CDK8CCNCCDK19 | |
| SCHEMBL16617783 | 0.75 | PTGER3 (0.69) | PTGER3CDK8CCNCCDK19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3055300-B1 | ANTAGONISTS OF PROSTAGLANDIN EP3 RECEPTOR | PFIZER (US) | 2018-03-07 | — | — | EP | disclosed |