SCHEMBL19944320

SCHEMBL19944320

CCn1ncc2c(F)cc(-c3ccc([C@]4(C)C(=O)NCCC4CCn4ncc5c(F)cc(-c6ccc([C@@]7(C)CCCNC7=O)c(=O)[nH]6)cc54)c(O)n3)cc21

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGER3 P43115 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19943981 0.93 PTGER3 (0.69) PTGER3
SCHEMBL16617864 0.83 PTGER3 (0.71) PTGER3
SCHEMBL16617863 0.83 PTGER3 (0.71) PTGER3
SCHEMBL16618064 0.83 PTGER3 (1.00) PTGER3
SCHEMBL16618065 0.83 PTGER3 (1.00) PTGER3
SCHEMBL19943992 0.80 PTGER3 (0.64) PTGER3
SCHEMBL19943958 0.78 PTGER3 (0.64) PTGER3
SCHEMBL16617262 0.76 PTGER3 (0.71) PTGER3
SCHEMBL16617260 0.76 PTGER3 (0.71) PTGER3
SCHEMBL16617128 0.75 PTGER3 (0.70) PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3055300-B1 ANTAGONISTS OF PROSTAGLANDIN EP3 RECEPTOR PFIZER (US) 2018-03-07 EP disclosed