SCHEMBL19944693

SCHEMBL19944693

N#Cc1c(-c2c[nH]c3ncncc23)nc(NC2C3CCC(CC3)[C@H]2C(=O)O)c(F)c1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.45
GSK3B P49841 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19944254 1.00 GSK3A (0.45) GSK3AGSK3B
SCHEMBL21117477 1.00 GSK3A (0.45) GSK3AGSK3B
SCHEMBL19944149 1.00 GSK3A (0.45) GSK3AGSK3B
SCHEMBL19944611 0.89 GSK3A (0.59) GSK3AGSK3B
SCHEMBL21117465 0.89 GSK3A (0.59) GSK3AGSK3B
SCHEMBL19944612 0.89 GSK3A (0.59) GSK3AGSK3B
SCHEMBL21117531 0.89 GSK3A (0.42) GSK3AGSK3B
SCHEMBL19944213 0.89 GSK3A (0.42) GSK3AGSK3B
SCHEMBL19944261 0.89 GSK3A (0.42) GSK3AGSK3B
SCHEMBL21117479 0.87 GSK3A (0.47) GSK3AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018041091-A1 INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF SUNSHINE LAKE PHARMA CO., LTD. (CN) 2018-03-08 WO disclosed