Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468149 | 1.00 | PTPRB (0.70) | PTPRBPTPN11 | |
| SCHEMBL20060120 | 0.88 | PTPRB (0.56) | PTPRB | |
| SCHEMBL500756 | 0.87 | PTPRB (0.69) | PTPRBPTPN11 | |
| SCHEMBL500755 | 0.87 | PTPRB (0.69) | PTPRBPTPN11 | |
| SCHEMBL28828118 | 0.85 | PTPRB (0.68) | PTPRBPTPN11 | |
| SCHEMBL27751528 | 0.84 | PTPRB (0.51) | PTPRB | |
| SCHEMBL27920724 | 0.84 | PTPRB (0.51) | PTPRB | |
| SCHEMBL16084739 | 0.84 | PTPRB (0.62) | PTPRBPTPN11 | |
| SCHEMBL10257243 | 0.83 | PTPRB (0.50) | PTPRB | |
| SCHEMBL468244 | 0.83 | PTPRB (0.61) | PTPRBPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3293182-A1 | HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE | Aerpio Therapeutics, Inc. (US) | 2018-03-14 | — | — | EP | disclosed |