Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19946018 | 0.80 | AAK1 (0.63) | AAK1 | |
| SCHEMBL20164872 | 0.79 | AAK1 (1.00) | AAK1 | |
| SCHEMBL20164871 | 0.79 | AAK1 (1.00) | AAK1 | |
| SCHEMBL21019120 | 0.77 | AAK1 (0.82) | AAK1 | |
| SCHEMBL21019157 | 0.76 | AAK1 (0.77) | AAK1 | |
| SCHEMBL21026449 | 0.76 | AAK1 (0.68) | AAK1 | |
| SCHEMBL21019115 | 0.76 | AAK1 (0.64) | AAK1 | |
| SCHEMBL19946160 | 0.76 | AAK1 (0.63) | AAK1 | |
| SCHEMBL21019114 | 0.75 | AAK1 (0.67) | AAK1 | |
| SCHEMBL21019124 | 0.75 | AAK1 (0.59) | AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3292124-A2 | FUSED PYRIDINES AS ADAPTOR ASSOCIATED KINASE 1 (AAK1) INHIBITORS | Bristol-Myers Squibb Company (US) | 2018-03-14 | — | — | EP | disclosed |