Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2724882 | 0.97 | TRPV1 (0.58) | TRPV1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL31679064 | 0.97 | TRPV1 (0.58) | TRPV1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL2724621 | 0.93 | TRPV1 (0.62) | TRPV1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL27666943 | 0.88 | TRPV1 (0.57) | TRPV1SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL2723775 | 0.87 | TRPV1 (0.55) | TRPV1KMT2AMAPTKDM4E | |
| SCHEMBL2726587 | 0.87 | TRPV1 (0.56) | TRPV1MAPTALDH1A1KDM4EFAAH | |
| SCHEMBL31679062 | 0.87 | TRPV1 (0.56) | TRPV1MAPTALDH1A1KDM4EFAAH | |
| SCHEMBL31679061 | 0.84 | TRPV1 (0.66) | TRPV1SMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL2725222 | 0.84 | TRPV1 (0.66) | TRPV1SMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL2725244 | 0.83 | TRPV1 (0.59) | TRPV1SMN1; SMN2MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635281-B1 | METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF CARDIAC HYPERTROPHY | UNIV HAWAII (US) | 2018-03-14 | — | — | EP | claimed |