SCHEMBL1995126

SCHEMBL1995126

CC[Si](CC)(CCOCC1CO1)OC

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.52
ALDH1A1 P00352 4/20 0.49
TDP1 Q9NUW8 1/20 0.49
TSHR P16473 2/20 0.48
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5268214 0.91 TSHR (0.54) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL611564 0.90 SMN1; SMN2 (0.58) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL614616 0.86 SMN1; SMN2 (0.58) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL1997261 0.84 SMN1; SMN2 (0.50) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL767110 0.82 SMN1; SMN2 (0.52) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL23521500 0.81 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL5266068 0.80 SMN1; SMN2 (0.53) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL614177 0.80 TSHR (0.61) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL432165 0.79 TSHR (0.54) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL5268562 0.79 TSHR (0.54) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4619451-A1 MODIFIED POLYMER POLYOLS Repsol, S.A. (ES) 2025-09-24 EP disclosed
WO-2025073830-A1 STABLE MODIFIED POLYMER POLYOL DISPERSIONS REPSOL, S.A. (ES) 2025-04-10 WO disclosed
WO-2024105080-A1 MODIFIED POLYMER POLYOLS REPSOL, S.A. (ES) 2024-05-23 WO disclosed
US-20210189053-A1 STABLE MODIFIED POLYMER POLYOL DISPERSIONS REPSOL, S.A. (ES) 2021-06-24 US disclosed
EP-3838962-A1 STABLE MODIFIED POLYMER POLYOL DISPERSIONS Repsol, S.A. (ES) 2021-06-23 EP disclosed
EP-2803699-B1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME BRIDGESTONE CORP (JP) 2018-09-12 EP disclosed
US-9623705-B2 Method for producing modified conjugated diene polymer/copolymer, modified conjugated diene polymer/copolymer, and rubber composition and tire using the same BRIDGESTONE CORPORATION (JP) 2017-04-18 US disclosed
US-9447208-B2 Rubber composition for tire, vulcanized rubber composition for tire, and tires using same BRIDGESTONE CORPORATION (JP) 2016-09-20 US disclosed
CN-104039884-B Rubber composition for tire, tire are with vulcanizate compositions and use its tire BRIDGESTONE CO.,LTD. (JP) 2016-05-18 CN disclosed
CN-102026826-B Process for producing modified conjugated diene polymer, and rubber composition and tire each produced using same BRIDGESTONE CORP 2015-01-14 CN disclosed
US-20140357804-A1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME BRIDGESTONE CORPORATION (JP) 2014-12-04 US disclosed
EP-2803699-A1 RUBBER COMPOSITION FOR TIRE, VULCANIZED RUBBER COMPOSITION FOR TIRE, AND TIRES USING SAME Bridgestone Corporation (JP) 2014-11-19 EP disclosed
CN-104039884-A Rubber composition for tire, vulcanized rubber composition for tire, and tires using same BRIDGESTONE CORP 2014-09-10 CN disclosed
EP-2266819-B1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME BRIDGESTONE CORP (JP) 2013-11-06 EP disclosed
US-20110146877-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed
CN-102026826-A Process for producing modified conjugated diene polymer, and rubber composition and tire each produced using same BRIDGESTONE CORP 2011-04-20 CN disclosed
EP-2266819-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, MODIFIED CONJUGATED DIENE POLYMER/COPOLYMER, AND RUBBER COMPOSITION AND TIER USING THE SAME Bridgestone Corporation (JP) 2010-12-29 EP disclosed