Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | HMGCR | P04035 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5684993 | 0.87 | TRPV1 (0.52) | POLBHMGCRNPSR1GAAALDH1A1 | |
| SCHEMBL3688663 | 0.87 | TRPV1 (0.52) | POLBHMGCRNPSR1GAAALDH1A1 | |
| SCHEMBL7827237 | 0.85 | NPSR1 (0.55) | POLBHMGCRNPSR1FFAR1FFAR4 | |
| SCHEMBL15354654 | 0.83 | NPSR1 (0.59) | POLBHMGCRNPSR1GAAALDH1A1 | |
| SCHEMBL30871956 | 0.81 | CYP3A4 (0.56) | POLBHMGCRNPSR1IMPDH2LMNA | |
| SCHEMBL490437 | 0.81 | CYP3A4 (0.56) | POLBHMGCRNPSR1IMPDH2LMNA | |
| SCHEMBL14441618 | 0.81 | POLB (0.51) | POLBHMGCRNPSR1FFAR1FFAR4 | |
| SCHEMBL3836319 | 0.80 | F13A1 (0.53) | POLBHMGCRGAAALDH1A1TSHR | |
| SCHEMBL30873959 | 0.79 | POLB (0.50) | POLBHMGCRNPSR1FFAR1FFAR4 | |
| SCHEMBL30871976 | 0.78 | NPSR1 (0.56) | POLBNPSR1ALDH1A1NFKB1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190233836-A1 | MEANS AND METHODS TO INCREASE COUMARIN PRODUCTION | VIB VZW (BE) | 2019-08-01 | — | — | US | disclosed |
| EP-3510158-A1 | MEANS AND METHODS TO INCREASE COUMARIN PRODUCTION | VIB VZW (BE) | 2019-07-17 | — | — | EP | disclosed |
| WO-2018046526-A1 | MEANS AND METHODS TO INCREASE COUMARIN PRODUCTION | VIB VZW (BE) | 2018-03-15 | — | — | WO | disclosed |