SCHEMBL19954095

CC(=O)OCC1C[C@H](n2cnc3c(=O)[nH]c(N)nc32)O[C@@H]1COP(=O)(O)O[C@@H]1C[C@H](n2cnc(N)nc2=O)O[C@@H]1COC(C)=O

nearest known ligand 0.54

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	POLB	P06746	1/20	0.54

▸	FUT5	Q11128	1/20	0.50

▸	P2RY2	P41231	1/20	0.48

▸	P2RY4	P51582	1/20	0.48

▸	P2RY6	Q15077	1/20	0.48

▸	NT5E	P21589	1/20	0.46

▸	P2RY1	P47900	1/20	0.46

▸	TGM2	P21980	1/20	0.45

▸	TAS1R3	Q7RTX0	1/20	0.44

▸	TAS1R1	Q7RTX1	1/20	0.44

▸	KRAS	P01116	3/20	0.44

▸	HINT1	P49773	1/20	0.44

▸	F2	P00734	2/20	0.43

▸	TERT	O14746	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21609617	0.95	POLB (0.54)	POLBFUT5P2RY2P2RY4P2RY6
SCHEMBL14750417	0.95	POLB (0.54)	POLBFUT5P2RY2P2RY4P2RY6
SCHEMBL14750407	0.95	POLB (0.54)	POLBFUT5P2RY2P2RY4P2RY6
SCHEMBL20924553	0.95	POLB (0.54)	POLBFUT5P2RY2P2RY4P2RY6
SCHEMBL20924348	0.95	POLB (0.54)	POLBFUT5P2RY2P2RY4P2RY6
SCHEMBL20924422	0.95	POLB (0.54)	POLBFUT5P2RY2P2RY4P2RY6
SCHEMBL21609618	0.95	POLB (0.54)	POLBFUT5P2RY2P2RY4P2RY6
SCHEMBL20832624	0.94	POLB (0.62)	POLBFUT5P2RY2P2RY4P2RY6
SCHEMBL20710405	0.94	POLB (0.62)	POLBFUT5P2RY2P2RY4P2RY6
SCHEMBL16156404	0.88	POLB (0.52)	POLBFUT5P2RY2P2RY4P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9913856-B2	Drug formulations	ASTEX PHARMACEUTICALS, INC. (US)	2018-03-13	—	—	US	disclosed