Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | BRD2 | P25440 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17433536 | 0.81 | BRD4 (0.68) | BRD4BRD2GAASMN1; SMN2PIK3CD | |
| SCHEMBL17433520 | 0.81 | BRD4 (0.68) | BRD4BRD2GAASMN1; SMN2PIK3CD | |
| SCHEMBL5254239 | 0.79 | BRD4 (0.59) | BRD4BRD2GAASMN1; SMN2PIK3CD | |
| SCHEMBL9020969 | 0.78 | — | — | |
| SCHEMBL158498 | 0.78 | — | — | |
| SCHEMBL22885435 | 0.73 | BRD4 (0.52) | BRD4BRD2GAASMN1; SMN2PIK3CD | |
| SCHEMBL17433534 | 0.72 | BRD4 (0.56) | BRD4BRD2GAASMN1; SMN2PIK3CD | |
| Methylpyrrolidone SCHEMBL8055062 | 0.70 | BRD4 (1.00) | BRD4BRD2GAASMN1; SMN2PIK3CD | |
| Methylpyrrolidone SCHEMBL487 | 0.70 | — | — | |
| Methylpyrrolidone SCHEMBL1255511 | 0.70 | BRD4 (1.00) | BRD4BRD2GAASMN1; SMN2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9913921-B2 | Pretargeting kit for imaging or therapy comprising a trans-cyclooctene dienophile and a diene | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2018-03-13 | — | — | US | disclosed |