Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.78 |
| ▸ | CNR1 | P21554 | 10/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17207906 | 0.89 | CNR2 (0.83) | CNR2CNR1 | |
| SCHEMBL15775151 | 0.89 | CNR2 (0.83) | CNR2CNR1 | |
| SCHEMBL15788854 | 0.88 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL15788905 | 0.87 | CNR2 (1.00) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL15774789 | 0.86 | CNR2 (0.98) | CNR2CNR1 | |
| SCHEMBL15775003 | 0.85 | CNR2 (0.75) | CNR2CNR1 | |
| SCHEMBL15774909 | 0.85 | CNR2 (0.86) | CNR2CNR1 | |
| SCHEMBL15774867 | 0.84 | CNR2 (0.69) | CNR2CNR1 | |
| SCHEMBL15774578 | 0.84 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL15774423 | 0.83 | CNR2 (0.80) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357918-A1 | NOVEL PYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2018-08-08 | — | — | EP | disclosed |
| EP-2928881-B1 | NOVEL PYRIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2018-03-14 | — | — | EP | disclosed |