Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.45 |
| ▸ | CLK1 | P49759 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 11/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22504129 | 0.78 | SMN1; SMN2 (0.34) | DYRK1ADYRK1BCLK1SMN1; SMN2 | |
| SCHEMBL663387 | 0.77 | — | — | |
| SCHEMBL980374 | 0.77 | — | — | |
| SCHEMBL1904974 | 0.77 | — | — | |
| SCHEMBL22694016 | 0.75 | — | — | |
| SCHEMBL21131580 | 0.74 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL24934339 | 0.72 | DYRK1A (0.45) | DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA | |
| SCHEMBL12676122 | 0.72 | DYRK1A (0.45) | DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA | |
| SCHEMBL10186549 | 0.72 | DYRK1A (0.45) | DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA | |
| SCHEMBL19957021 | 0.72 | DYRK1A (0.45) | DYRK1ADYRK1BCLK1SMN1; SMN2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3293242-A1 | COMPOSITIONS COMPRISING HFC-1234YF | The Chemours Company FC, LLC (US) | 2018-03-14 | — | — | EP | disclosed |