Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | INPP5D | Q92835 | 2/20 | 0.64 |
| ▸ | NPC1L1 | Q9UHC9 | 5/20 | 0.63 |
| ▸ | POLA1 | P09884 | 2/20 | 0.57 |
| ▸ | TOP2A | P11388 | 1/20 | 0.57 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.50 |
| ▸ | FNTA | P49354 | 2/20 | 0.48 |
| ▸ | FNTB | P49356 | 2/20 | 0.48 |
| ▸ | CDC25A | P30304 | 3/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12806705 | 0.87 | POLA1 (0.74) | CYP2D6CYP2C19INPP5DNPC1L1POLA1 | |
| SCHEMBL19494787 | 0.85 | NPC1L1 (0.56) | CYP2D6CYP2C19INPP5DNPC1L1POLA1 | |
| SCHEMBL27573811 | 0.84 | NPC1L1 (0.62) | CYP2D6CYP2C19INPP5DNPC1L1POLA1 | |
| SCHEMBL17817335 | 0.81 | CYP2D6 (0.76) | CYP2D6CYP2C19INPP5DNPC1L1POLA1 | |
| SCHEMBL17817080 | 0.81 | NPC1L1 (0.82) | CYP2D6CYP2C19INPP5DNPC1L1POLA1 | |
| SCHEMBL18071941 | 0.80 | NPC1L1 (0.59) | CYP2D6CYP2C19INPP5DNPC1L1POLA1 | |
| SCHEMBL24104745 | 0.79 | NPC1L1 (0.83) | CYP2D6CYP2C19INPP5DNPC1L1USP2 | |
| SCHEMBL8492231 | 0.79 | NPC1L1 (0.67) | CYP2D6CYP2C19INPP5DNPC1L1POLA1 | |
| SCHEMBL17817325 | 0.79 | NPC1L1 (0.83) | CYP2D6CYP2C19INPP5DNPC1L1USP2 | |
| SCHEMBL17817328 | 0.79 | NPC1L1 (0.83) | CYP2D6CYP2C19INPP5DNPC1L1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3293195-A1 | COMPOUNDS FOR USE IN TREATING DIABETES | OHR Pharmaceutical, Inc. (US) | 2018-03-14 | — | — | EP | disclosed |