Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17975131 | 0.85 | MAPT (0.81) | MAPT | |
| SCHEMBL16634186 | 0.85 | MAPT (0.81) | MAPT | |
| SCHEMBL29598856 | 0.85 | MAPT (0.81) | MAPT | |
| SCHEMBL17967652 | 0.84 | MAPT (0.68) | MAPT | |
| SCHEMBL17967629 | 0.83 | MAPT (1.00) | MAPT | |
| SCHEMBL19958143 | 0.82 | MAPT (0.65) | MAPT | |
| SCHEMBL17967573 | 0.82 | MAPT (1.00) | MAPT | |
| SCHEMBL29475856 | 0.82 | MAPT (1.00) | MAPT | |
| SCHEMBL16943219 | 0.81 | MAPT (0.62) | MAPT | |
| SCHEMBL22906765 | 0.81 | MAPT (0.67) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3510031-B1 | PROCESS FOR PREPARATION OF 2-(6-NITROPYRIDIN-3-YL)-9H-DIPYRIDO[2,3-B;3',4'-D]PYRROLE | HOFFMANN LA ROCHE (CH) | 2020-12-02 | — | — | EP | disclosed |
| WO-2018046428-A1 | PROCESS FOR PREPARATION OF 2-(6-NITROPYRIDIN-3-YL)-9H-DIPYRIDO[2,3-B;3',4'-D]PYRROLE | F. HOFFMANN-LA ROCHE AG (CH) | 2018-03-15 | — | — | WO | disclosed |