Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19959626 | 0.89 | NT5E (0.76) | NT5E | |
| SCHEMBL19959517 | 0.88 | NT5E (0.75) | NT5E | |
| SCHEMBL20305236 | 0.88 | NT5E (1.00) | NT5E | |
| SCHEMBL19959546 | 0.87 | NT5E (0.88) | NT5E | |
| SCHEMBL19959450 | 0.87 | NT5E (0.84) | NT5E | |
| SCHEMBL20333800 | 0.87 | NT5E (0.84) | NT5E | |
| SCHEMBL24835864 | 0.86 | NT5E (0.84) | NT5E | |
| SCHEMBL20333901 | 0.86 | NT5E (0.76) | NT5E | |
| SCHEMBL20334156 | 0.86 | NT5E (0.76) | NT5E | |
| SCHEMBL24026331 | 0.86 | NT5E (0.76) | NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018119284-A1 | ECTONUCLEOTIDASE INHIBITORS AND METHODS OF USE THEREOF | CALITHERA BIOSCIENCES, INC. (US) | 2018-06-28 | — | — | WO | disclosed |
| WO-2018049145-A1 | ECTONUCLEOTIDASE INHIBITORS AND METHODS OF USE THEREOF | CALITHERA BIOSCIENCES, INC. (US) | 2018-03-15 | — | — | WO | disclosed |