Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 15/20 | 0.68 |
| ▸ | CD99 | P14209 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19949327 | 0.86 | NT5E (0.51) | NT5ECD99ADORA3 | |
| SCHEMBL20333709 | 0.85 | NT5E (0.56) | NT5E | |
| SCHEMBL30262574 | 0.85 | NT5E (0.56) | NT5E | |
| SCHEMBL19961924 | 0.84 | NT5E (0.48) | NT5ECD99ADORA3 | |
| SCHEMBL30262553 | 0.81 | NT5E (0.71) | NT5ECD99ADORA1 | |
| SCHEMBL19948958 | 0.81 | NT5E (1.00) | NT5ECD99 | |
| SCHEMBL19949062 | 0.81 | NT5E (1.00) | NT5ECD99 | |
| SCHEMBL30262580 | 0.81 | NT5E (1.00) | NT5ECD99 | |
| SCHEMBL19948652 | 0.81 | NT5E (1.00) | NT5ECD99 | |
| SCHEMBL30262592 | 0.81 | NT5E (1.00) | NT5ECD99 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018049145-A1 | ECTONUCLEOTIDASE INHIBITORS AND METHODS OF USE THEREOF | CALITHERA BIOSCIENCES, INC. (US) | 2018-03-15 | — | — | WO | disclosed |