Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30115091 | 0.84 | NT5E (0.81) | NT5E | |
| SCHEMBL19948669 | 0.84 | NT5E (0.81) | NT5E | |
| SCHEMBL19968991 | 0.81 | NT5E (0.57) | NT5E | |
| SCHEMBL24835627 | 0.79 | NT5E (0.62) | NT5E | |
| SCHEMBL24026316 | 0.76 | NT5E (0.57) | NT5E | |
| SCHEMBL19968750 | 0.74 | NT5E (0.70) | NT5E | |
| SCHEMBL19948668 | 0.74 | NT5E (1.00) | NT5E | |
| SCHEMBL30115135 | 0.73 | NT5E (0.80) | NT5E | |
| SCHEMBL19948409 | 0.73 | NT5E (0.80) | NT5E | |
| SCHEMBL19968659 | 0.70 | NT5E (0.55) | NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018049145-A1 | ECTONUCLEOTIDASE INHIBITORS AND METHODS OF USE THEREOF | CALITHERA BIOSCIENCES, INC. (US) | 2018-03-15 | — | — | WO | disclosed |