Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19953613 | 0.99 | TSHR (0.62) | TSHRNPSR1OPRM1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL19953790 | 0.99 | TSHR (0.62) | TSHRNPSR1OPRM1SLC6A2SLC6A4 | |
| SCHEMBL5160890 | 0.82 | TSHR (0.67) | TSHRNPSR1OPRM1SLC6A2SLC6A4 | |
| SCHEMBL32689446 | 0.82 | TSHR (0.67) | TSHRNPSR1OPRM1SLC6A2SLC6A4 | |
| SCHEMBL13646900 | 0.81 | TSHR (0.65) | TSHRNPSR1OPRM1SLC6A2SLC6A4 | |
| SCHEMBL6091166 | 0.79 | TSHR (0.55) | TSHRNPSR1OPRM1SLC6A2SLC6A4 | |
| SCHEMBL11104021 | 0.78 | TSHR (0.66) | TSHRNPSR1OPRM1SLC6A2SLC6A4 | |
| SCHEMBL4022286 | 0.78 | TSHR (0.75) | TSHRNPSR1OPRM1SLC6A2SLC6A4 | |
| SCHEMBL19960812 | 0.77 | TSHR (0.50) | TSHRNPSR1OPRM1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL11481488 | 0.77 | TSHR (0.68) | TSHRNPSR1OPRM1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018047983-A1 | INDANE DERIVATIVES USEFUL AS MODULATORS OF MGLUR7 | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-03-15 | — | — | WO | disclosed |