Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 20/20 | 0.58 |
| ▸ | RBBP4 | Q09028 | 20/20 | 0.58 |
| ▸ | SUZ12 | Q15022 | 20/20 | 0.58 |
| ▸ | EZH2 | Q15910 | 20/20 | 0.58 |
| ▸ | AEBP2 | Q6ZN18 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19964957 | 0.90 | EED (0.55) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964824 | 0.89 | EED (0.56) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964392 | 0.88 | EED (0.57) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113449 | 0.87 | EED (0.47) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964403 | 0.87 | EED (0.58) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964449 | 0.86 | EED (0.59) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113379 | 0.86 | EED (0.60) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113495 | 0.85 | EED (0.61) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964471 | 0.85 | EED (0.46) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964908 | 0.84 | EED (0.49) | EEDRBBP4SUZ12EZH2AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3524602-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Haihe Pharmaceutical Co., Ltd. (CN) | 2019-08-14 | — | — | EP | disclosed |
| WO-2018045971-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海海和药物研究开发有限公司 | 2018-03-15 | — | — | WO | disclosed |