Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.54 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.47 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1993317 | 0.89 | MAPK14 (0.67) | MAPK14MAPK11MAPK13MAPK12 | |
| SCHEMBL1997890 | 0.84 | MAPK14 (0.55) | MAPK14MAPK11MAPK13MAPK12RIPK3 | |
| SCHEMBL1995963 | 0.82 | MAPK14 (0.52) | MAPK14MAPK11MAPK13MAPK12RIPK3 | |
| SCHEMBL1998934 | 0.80 | MAPK14 (0.48) | MAPK14RIPK3 | |
| SCHEMBL1995055 | 0.80 | RIPK3 (0.58) | MAPK14MAPK11MAPK13MAPK12RIPK3 | |
| SCHEMBL1994116 | 0.80 | MAPK14 (0.70) | MAPK14MAPK11MAPK13MAPK12RIPK3 | |
| SCHEMBL2001207 | 0.80 | QPCT (0.48) | MAPK14MAPK11MAPK13MAPK12RIPK3 | |
| SCHEMBL1994450 | 0.76 | MAPK14 (0.67) | MAPK14MAPK11MAPK13MAPK12RIPK3 | |
| SCHEMBL1995955 | 0.75 | MAPK14 (0.43) | MAPK14MAPK11MAPK13MAPK12RIPK3 | |
| SCHEMBL1996343 | 0.74 | MAPK14 (0.43) | MAPK14MAPK11MAPK13MAPK12RIPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338890-A1 | 4,7-Diazaindole derivatives and their use as fungicides | Bayer CropScience AG (DE) | 2011-06-29 | — | — | EP | claimed |
| EP-2338890-A1 | 4,7-Diazaindole derivatives and their use as fungicides | Bayer CropScience AG (DE) | 2011-06-29 | — | — | EP | disclosed |