Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 17/20 | 0.47 |
| ▸ | RBBP4 | Q09028 | 17/20 | 0.47 |
| ▸ | SUZ12 | Q15022 | 17/20 | 0.47 |
| ▸ | EZH2 | Q15910 | 17/20 | 0.47 |
| ▸ | AEBP2 | Q6ZN18 | 17/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19964461 | 0.91 | EED (0.46) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964798 | 0.87 | EED (0.52) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21157382 | 0.86 | EED (0.64) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113127 | 0.85 | EED (0.51) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964895 | 0.85 | EED (0.64) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21113439 | 0.85 | EED (0.50) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL21156604 | 0.85 | EED (0.52) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964971 | 0.85 | EED (0.64) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964987 | 0.85 | EED (0.56) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL19964889 | 0.85 | EED (0.52) | EEDRBBP4SUZ12EZH2AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045971-A1 | PYRIDO FIVE-ELEMENT AROMATIC RING COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海海和药物研究开发有限公司 | 2018-03-15 | — | — | WO | disclosed |