⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23746681 | 0.71 | — | — | |
| SCHEMBL18968484 | 0.71 | — | — | |
| SCHEMBL18969115 | 0.71 | — | — | |
| SCHEMBL18968310 | 0.71 | — | — | |
| SCHEMBL19043111 | 0.69 | SLC1A2 (0.31) | — | |
| SCHEMBL2186226 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL2186105 | 0.64 | — | — | |
| SCHEMBL14369950 | 0.59 | — | — | |
| SCHEMBL17751200 | 0.57 | — | — | |
| SCHEMBL25765537 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357158-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2023-11-09 | — | — | US | disclosed |
| US-20180072744-A1 | HETEROARYL SYK INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2018-03-15 | — | — | US | disclosed |