Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 14/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990891 | 0.85 | PTGDR2 (0.52) | PTGDR2MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL1990890 | 0.85 | PTGDR2 (0.52) | PTGDR2MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL1992159 | 0.85 | PTGDR2 (0.75) | PTGDR2RAB9ASMN1; SMN2 | |
| SCHEMBL5315714 | 0.83 | PTGDR2 (0.75) | PTGDR2NPC1MAPTRAB9A | |
| SCHEMBL1997245 | 0.81 | PTGDR2 (0.69) | PTGDR2NPC1RAB9A | |
| SCHEMBL1996077 | 0.77 | PTGDR2 (0.53) | PTGDR2MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL1997071 | 0.76 | PTGDR2 (0.76) | PTGDR2 | |
| SCHEMBL1993265 | 0.76 | PTGDR2 (0.77) | PTGDR2 | |
| SCHEMBL1997428 | 0.74 | PTGDR2 (0.75) | PTGDR2NPC1RAB9A | |
| SCHEMBL12159870 | 0.74 | PTGDR2 (0.57) | PTGDR2MEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336113-A1 | CRTH2 Receptor Ligands for Medical Use | 7TM Pharma A/S (DK) | 2011-06-22 | — | — | EP | disclosed |