⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethanesulfonic Acid Amide SCHEMBL28038 | 0.95 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL27416092 | 0.91 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL3402460 | 0.91 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL27673482 | 0.91 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL3480490 | 0.91 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL9859651 | 0.91 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL2883670 | 0.91 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL27765064 | 0.91 | — | — | |
| Ethanesulfonic Acid Amide SCHEMBL28039728 | 0.87 | — | — | |
| Sulfamide SCHEMBL17923148 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516420-A1 | AMINOALKYLPYRIMIDINE DERIVATIVES AS HISTAMINE H4 RECEPTOR ANTAGONISTS | Palau Pharma, S.A. (ES) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011076878-A1 | AMINOALKYLPYRIMIDINE DERIVATIVES AS HISTAMINE H4 RECEPTOR ANTAGONISTS | PALAU PHARMA, S.A. (ES) | 2011-06-30 | — | — | WO | disclosed |