Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630862 | 0.87 | PARP1 (1.00) | PARP1PARP2 | |
| SCHEMBL631188 | 0.86 | PARP1 (0.81) | PARP1PARP2 | |
| Hydrochloric Acid SCHEMBL18497043 | 0.85 | PARP1 (0.79) | PARP1PARP2 | |
| Hydrochloric Acid SCHEMBL18497042 | 0.85 | PARP1 (0.79) | PARP1PARP2 | |
| SCHEMBL659464 | 0.85 | PARP1 (0.57) | PARP1PARP2 | |
| SCHEMBL631014 | 0.84 | PARP1 (0.94) | PARP1PARP2 | |
| SCHEMBL630263 | 0.84 | PARP1 (0.94) | PARP1PARP2 | |
| SCHEMBL660171 | 0.82 | PARP1 (0.56) | PARP1PARP2 | |
| SCHEMBL656635 | 0.82 | PARP1 (0.56) | PARP1PARP2 | |
| SCHEMBL630282 | 0.82 | PARP1 (0.76) | PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338487-B1 | Combination therapy with PARP inhibitors | ABBOTT LAB (US) | 2013-09-11 | — | — | EP | disclosed |
| EP-2338487-A1 | Combination therapy with PARP inhibitors | Abbott Laboratories (US) | 2011-06-29 | — | — | EP | disclosed |