Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 19/20 | 0.70 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | GIPR | P48546 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19922820 | 0.93 | GCGR (0.81) | GCGRGIPR | |
| SCHEMBL19922841 | 0.90 | GCGR (0.67) | GCGRGIPR | |
| SCHEMBL19922788 | 0.89 | GCGR (0.61) | GCGR | |
| SCHEMBL19922811 | 0.87 | GCGR (0.78) | GCGRGIPR | |
| SCHEMBL19922764 | 0.86 | GCGR (0.77) | GCGRGIPR | |
| SCHEMBL19922822 | 0.85 | GCGR (0.86) | GCGR | |
| SCHEMBL19922869 | 0.84 | GCGR (0.64) | GCGRGIPR | |
| SCHEMBL19922776 | 0.84 | GCGR (0.79) | GCGR | |
| SCHEMBL19922818 | 0.84 | GCGR (0.63) | GCGRGIPR | |
| SCHEMBL19922855 | 0.83 | GCGR (0.69) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018048761-A1 | INDOLE DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2018-03-15 | — | — | WO | disclosed |